PacBio Expands Partnership with seqWell: A Leap Forward in Genomic Research
On October 7, 2025, Pacific Biosciences of California Inc. (PacBio), a leader in high-accuracy sequencing solutions, announced an expanded partnership with seqWell, a prominent provider of genomic library and multiplexing workflow solutions. This new collaboration aims to enhance the accessibility and efficiency of long-read sample preparation for genomic researchers around the globe.
1. Introducing the LongPlex™ Multiplexing Kit
The cornerstone of this partnership is the LongPlex™ Multiplexing Kit, an innovative sample preparation solution that facilitates the use of PacBio’s HiFi sequencing technology. This kit is designed to streamline the often cumbersome sample preparation process, enabling researchers to produce high-quality libraries more rapidly and cost-effectively. By removing sample prep bottlenecks, the LongPlex kit empowers researchers to engage in population-scale studies and large-scale genomic screening with greater ease.
The LongPlex™ kit employs a transposase-based DNA fragmentation method known as tagmentation, allowing for simultaneous fragmentation and indexing of DNA across hundreds of samples in a single run. This feature makes it particularly useful for large-scale genomic projects, including targeted resequencing efforts.
2. A Commitment to Flexibility and Efficiency
David Miller, PacBio's Vice President of Global Marketing, emphasized the company's commitment to providing researchers with the flexibility and speed required for modern genomic studies. "Expanding our partnership with seqWell is part of our commitment to meet researchers where they are with the flexibility, speed, and accuracy they need," Miller stated. The introduction of LongPlex alongside existing workflows enhances the options available to PacBio customers, particularly in high-throughput applications where rapid and economical data generation is crucial.
3. Real-World Applications and Endorsements
Organizations such as Veil Genomics are already leveraging the LongPlex™ Multiplexing Kit to advance their genomic initiatives. Dr. Josh Clevenger, Co-founder of Veil Genomics, highlighted how the kit supports their low-pass whole genome sequencing (WGS) workflow, allowing them to process thousands of samples without compromising data quality. "At Veil, our goal is to democratize genomic insights through scalable, cost-effective data," Clevenger remarked, showcasing the practical impact of the LongPlex kit in real-world applications.
The LongPlex™ Multiplexing Kit is designed to support a variety of genomic workflows, including low-pass WGS, plasmid sequencing, and microbial sequencing. Its streamlined indexed tagmentation workflow is characterized by reduced hands-on time while ensuring the high-quality data performance that researchers require.
4. A Vision for Accelerating Discovery
Dan Calvo, President and CEO of seqWell, expressed excitement about the expanded collaboration, stating, "We’re proud to expand our collaboration with PacBio, bringing LongPlex™ to more labs worldwide." This agreement reflects a shared vision between the two companies to accelerate genomic discovery by making innovative and practical sample preparation tools more accessible to researchers.
The LongPlex™ Multiplexing Kit is available for purchase today, with global availability expected in 2026, marking a significant addition to PacBio’s suite of sequencing solutions.
5. Conclusion
The expanded partnership between PacBio and seqWell represents a significant advancement in genomic research capabilities. By offering the LongPlex™ Multiplexing Kit, the collaboration aims to enhance the efficiency and scalability of sample preparation in genomic studies, ultimately driving forward the field of genomics and enabling more researchers to participate in groundbreaking discoveries. As the demand for high-quality genomic data continues to grow, innovations like LongPlex will play a pivotal role in shaping the future of genomic research. For further information about the LongPlex™ Multiplexing Kit and its compatible workflows, researchers are encouraged to visit PacBio's official website.