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Arcutis Biotherapeutics, Inc. (ARQT)
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Arcutis Biotherapeutics Set to Showcase Key Research at AAD Annual Meeting

Last updated: February 28, 2025
Taurigo

Arcutis Biotherapeutics, Inc. (Nasdaq: ARQT), a prominent player in the field of immuno-dermatology, has announced its participation in the 83rd American Academy of Dermatology (AAD) Annual Meeting, scheduled for March 7-11, 2025, in Orlando, Florida. The company will present critical data through two posters that highlight advancements in the treatment of atopic dermatitis (AD) and psoriasis.

1. Presentation Highlights

Pooled Safety Data from Phase 3 Trials

The first poster presentation will focus on pooled safety and local tolerability data for roflumilast cream 0.15%. This research stems from the INTEGUMENT-1 and INTEGUMENT-2 Phase 3 trials and targets adults and children as young as six who have previously experienced inadequate responses, intolerance, or contraindications to topical treatments, including topical steroids.

Poster Details:

  • Title: Pooled Safety and Local Tolerability of Roflumilast Cream 0.15% from the INTEGUMENT-1 and INTEGUMENT-2 Phase 3 Trials of Patients With Atopic Dermatitis: Subgroup Analysis of Patients With Prior Inadequate Response, Intolerance, and/or Contraindications to Topical Treatments
  • Authors: Simpson, E et al.
  • Poster Number: 62155

Significant Improvements in Psoriasis Outcomes

The second poster will detail findings from the ARRECTOR trial, showcasing the significant improvements in patient-reported outcomes related to roflumilast foam 0.3%. This presentation highlights the efficacy of the foam in treating scalp and body psoriasis in individuals over the age of 12.

Poster Details:

  • Title: Roflumilast Foam 0.3% in Patients With Scalp and Body Psoriasis: Improvements in Patient-Reported Outcomes (ARRECTOR)
  • Authors: Gooderham, M et al.
  • Poster Number: 62151

2. Insights from Leadership

Patrick Burnett, MD, PhD, FAAD, Arcutis’ Chief Medical Officer, expressed enthusiasm about presenting this data, stating, “Highlighting additional data from our clinical development program for ZORYVE foam in scalp and body psoriasis and ZORYVE cream in atopic dermatitis reinforces the strong need for well-tolerated treatments among diverse patient populations, including those intolerant to steroids or who have had an inadequate response.” Burnett expressed confidence that these treatments may significantly improve the lives of individuals suffering from chronic inflammatory skin conditions.

3. Culturally Conscious Dermatology Initiative

In addition to the poster presentations, Arcutis will host two experiential learning sessions at its booth (Booth 1361) in collaboration with Dr. Candrice Heath of the Heath Health Foundation for Education and Research. These sessions will focus on Culturally Conscious Dermatology™, providing attendees with valuable insights into culturally sensitive dermatological care and scalp examination techniques.

Session Schedule:

  • Friday, March 7: 3:00 PM EST
  • Saturday, March 8: 2:30 PM EST

4. About ZORYVE (roflumilast)

ZORYVE is a next-generation topical phosphodiesterase-4 (PDE4) inhibitor, targeting chronic inflammatory skin conditions. The cream formulations, including roflumilast cream 0.3% and roflumilast cream 0.15%, have received FDA approval for the treatment of plaque psoriasis and mild to moderate atopic dermatitis, respectively. Additionally, ZORYVE foam is approved for seborrheic dermatitis in patients aged nine and older, with further indications for scalp and body psoriasis currently under FDA review.

5. Company Overview

Arcutis Biotherapeutics is dedicated to innovating in the field of medical dermatology, addressing the urgent needs of patients suffering from immune-mediated dermatological diseases. With a growing portfolio of FDA-approved products and a robust pipeline targeting various skin conditions, Arcutis is well-positioned to impact the landscape of dermatological care.

The AAD Annual Meeting presents an opportunity for Arcutis to share its latest findings and engage with the dermatology community, reinforcing its commitment to advancing patient care and treatment efficacy in the realm of dermatology.

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